The endocannabinoid system is a complex network of cellular neurotransmitter receptors (called CB1 and CB2) that are responsible for maintaining homeostasis in the body. The greatest number of CB1 receptors are found in the brain, while CB2 receptors are more commonly found in immune cells, the gastrointestinal tract, and the peripheral nervous system. The diversity of receptor locations shows how important endocannabinoids are for the body's daily function.
The ECS controls a wide range of biological functions, including sleep, mood, temperature regulation, immune response, perception of pain and pleasure, fertility, memory, and appetite.
Research links the endocannabinoid system to many activities, such as:
- Stimulating the appetite and supporting digestion
- Regulation of metabolism
- Influencing mood
- Improving learning and memory
- Control of motor movements
- support for better sleep
- Maintaining the function of the cardiovascular system
- Muscle building support
- Help in bone remodeling and growth
- Regulation of liver function
- Facilitating the function of the reproductive system
- Support of skin and nerve function
Whenever something happens to your health, the endocannabinoid system releases its natural cannabinoids (endocannabinoids) to restore balance in the body. If the body does not produce enough endocannabinoids or cannot regulate them properly, you are more susceptible to diseases that affect one or more of the above functions.
What is the relationship between THC and the endocannabinoid system?
The main psychoactive element of marijuana is tetrahydrocannabinol (THC). It is this compound that creates the feeling of "rausch". THC present in the body interacts with the endocannabinoid system by attaching to receptors similar to endocannabinoids. Its potency is due in part to its ability to bind to both CB1 and CB2 receptors. The effects of THC on your body and mind can vary. In some cases, it can help relieve pain and increase appetite. On the other hand, it can also cause feelings of paranoia and anxiety.
Experts are currently exploring approaches to create synthetic THC cannabinoids that interact with the endocannabinoid system in only beneficial ways.
How does CBD interact with the endocannabinoid system?
Another cannabinoid contained in hemp is cannabidiol (CBD), which does not have psychoactive effects like THC and is not known to cause adverse reactions.
CBD does not act directly on cannabinoid receptors (CB1 and CB2), but instead stimulates the endocannabinoid system to produce its own cannabinoids. It is assumed that CBD inhibits the degradation of endocannabinoids, which results in a more pronounced effect on the human body. In addition, it is speculated that the cannabinoid may bind to a receptor that has not yet been identified. The key lies in the correct doses of CBD, tailored to the needs of the client.
CBD is a remarkably complex cannabinoid and its interaction with the endocannabinoid system needs to be further explored to reveal its full potential.
What can cause a lack of endocannabinoids?
Some experts accept the idea of clinical endocannabinoid deficiency (CECD). This assumption is that diseases can be caused by a lack of endocannabinoid levels in the body or a malfunction of the ECS. An Analysis of more than a decade of studies published in 2016 suggests that this theory could be the reason why some people suffer from migraines, fibromyalgia and irritable bowel syndrome. A single source cannot be determined for any of these circumstances. In addition, they usually do not respond to treatment and sometimes appear simultaneously. The answer to this question could be the endocannabinoid system (ECS) or the production of endocannabinoids, but more research is needed to confirm this fact.
The endocannabinoid system (ECS) is a complex biological system that plays a key role in maintaining balance in the body. The ECS consists of endocannabinoids, a receptor that binds to them, and enzymes that secrete and degrade them. Endocannabinoids are molecules produced in the body that act as signaling substances between cells to ensure homeostasis.
Currently, much is still unknown about ECS and its functions. However, thanks to advanced research, experts are beginning to better understand how this system works and how it can influence various physical and psychological processes. Therefore, it turns out that a properly functioning ECS can be a potential solution for various diseases, such as headaches, anxiety, depression, addictions, etc.